Abstract The subject of the present thesis is the evaluation of a biocompatible, biodegradable and highly filled resin for stereolithography consisting of tricalciumphosphate, multifunctional thiols and bifunctional alkynes. This includes the synthesis of bifunctional alkynes, the investigations of the shelf life, the photo reactivity, and the 3d printability of the Thiol-yne system by stereolithography. The photo polymers are investigated concerning mechanical properties, biodegradability and migration of low-molecular substances. Therefore, bifunctional alkynes were synthesized, and a formulation of the thiol-in-system has been worked out. The shelf life of the formulation was investigated by measuring the increase of the viscosity. To characterise the curing behaviour of the resin, real time Fourier-transformed infrared spectroscopy and photo differential scanning calorimetry measurements were conducted. The migration behaviour of low-molecular substances in the photo polymer were analysed by means of mass chromatography. Mechanical properties of the photo polymer were measured by uniaxial tensile tests and dynamic mechanical analysis. Further the degradability of the photopolymer was investigated in basic medium. In the course of this thesis the feasability to stabilise the highly filled thiol-yne-system for several weeks could be shown. It is possible to process the unfilled resin with a standard SLA-printer whereas filled systems could only be processed by stereolithograph with a recoater due to the high viscosity of the resin. The obtained polymer could be degraded completely. The composites show low migration behaviour and therefore they promise high potential for an application in medical devices.
|Translated title of the contribution
|Investigation of the Thiol-Yne Monomer System for the 3D Printing of Biocompatible Composite Structures
|19 Oct 2018
|Published - 2018
Bibliographical noteembargoed until null
- photo polymerisation