Hybrid Structures for Surface-Enhanced Raman Scattering: DNA Origami/Gold Nanoparticle Dimer/Graphene

Julia Prinz, Aleksandar Matkovic, Jelena Pesic, Radoš Gajić, Ilko Bald

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)


A combination of three innovative materials within one hybrid structure to explore the synergistic interaction of their individual properties is presented. The unique electronic, mechanical, and thermal properties of graphene are combined with the plasmonic properties of gold nanoparticle (AuNP) dimers, which are assembled using DNA origami nanostructures. This novel hybrid structure is characterized by means of correlated atomic force microscopy and surface-enhanced Raman scattering (SERS). It is demonstrated that strong interactions between graphene and AuNPs result in superior SERS performance of the hybrid structure compared to their individual components. This is particularly evident in efficient fluorescence quenching, reduced background, and a decrease of the photobleaching rate up to one order of magnitude. The versatility of DNA origami structures to serve as interface for complex and precise arrangements of nanoparticles and other functional entities provides the basis to further exploit the potential of the here presented DNA origami–AuNP dimer–graphene hybrid structures.
Original languageEnglish
Article number201601908
Pages (from-to)5458-5467
Number of pages10
Issue number39
Publication statusPublished - 4 Oct 2016


  • SERS
  • graphene
  • DNA origami

Cite this