Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering

Publikationen: Beitrag in FachzeitschriftArtikelForschung(peer-reviewed)

Standard

Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering. / Rashid, Saqib; Vita, Gian Marco; Persichetti, Luca; Iucci, Giovanna; Battocchio, Chiara; Daniel, Rostislav; Visaggio, Daniela; Marsotto, Martina; Visca, Paolo; Bemporad, Edoardo; Ascenzi, Paolo; Capellini, Giovanni; Sebastiani, Marco; di Masi, Alessandra.

in: Applied surface science, Jahrgang 573.2022, Nr. 30 January, 151604, 30.01.2022.

Publikationen: Beitrag in FachzeitschriftArtikelForschung(peer-reviewed)

Harvard

Rashid, S, Vita, GM, Persichetti, L, Iucci, G, Battocchio, C, Daniel, R, Visaggio, D, Marsotto, M, Visca, P, Bemporad, E, Ascenzi, P, Capellini, G, Sebastiani, M & di Masi, A 2022, 'Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering', Applied surface science, Jg. 573.2022, Nr. 30 January, 151604. https://doi.org/10.1016/j.apsusc.2021.151604

APA

Rashid, S., Vita, G. M., Persichetti, L., Iucci, G., Battocchio, C., Daniel, R., Visaggio, D., Marsotto, M., Visca, P., Bemporad, E., Ascenzi, P., Capellini, G., Sebastiani, M., & di Masi, A. (2022). Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering. Applied surface science, 573.2022(30 January), [151604]. https://doi.org/10.1016/j.apsusc.2021.151604

Author

Rashid, Saqib ; Vita, Gian Marco ; Persichetti, Luca ; Iucci, Giovanna ; Battocchio, Chiara ; Daniel, Rostislav ; Visaggio, Daniela ; Marsotto, Martina ; Visca, Paolo ; Bemporad, Edoardo ; Ascenzi, Paolo ; Capellini, Giovanni ; Sebastiani, Marco ; di Masi, Alessandra. / Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering. in: Applied surface science. 2022 ; Jahrgang 573.2022, Nr. 30 January.

Bibtex - Download

@article{fdfecdf56d3e4bbfaf416c8db874215f,
title = "Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering",
abstract = "Mechanical robustness, biocompatibility, and antibacterial performance are key features for materials suitable to be used in tissue engineering applications. In this work, we investigated the link existing between structural and functional properties of TiCu(Ag) thin films deposited by physical vapor deposition magnetron sputtering (MS-PVD) on Si substrates. Thin films were characterized by X-ray diffraction (XRD), nanoindentation, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). The TiCu(Ag) films showed complete amorphous structure and improved mechanical properties in comparison with pure Ti films. However, for contents in excess of 20% Ag we observed the appearance of nanometric Ag crystallite. The TiCu(Ag) thin films displayed excellent biocompatibility properties, allowing adhesion and proliferation of the human fibroblasts MRC-5 cell line. Moreover, all the investigated TiCu(Ag) alloys display bactericidal properties, preventing the growth of both Pseudomonas aeruginosa and Staphylococcus aureus. Results obtained from biological tests have been correlated to the surface structure and microstructure of films. The excellent biocompatibility and bactericidal properties of these multifunctional thin films opens to their use in tissue engineering applications.",
author = "Saqib Rashid and Vita, {Gian Marco} and Luca Persichetti and Giovanna Iucci and Chiara Battocchio and Rostislav Daniel and Daniela Visaggio and Martina Marsotto and Paolo Visca and Edoardo Bemporad and Paolo Ascenzi and Giovanni Capellini and Marco Sebastiani and {di Masi}, Alessandra",
note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",
year = "2022",
month = jan,
day = "30",
doi = "10.1016/j.apsusc.2021.151604",
language = "English",
volume = "573.2022",
journal = "Applied surface science",
issn = "0169-4332",
publisher = "Elsevier",
number = "30 January",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering

AU - Rashid, Saqib

AU - Vita, Gian Marco

AU - Persichetti, Luca

AU - Iucci, Giovanna

AU - Battocchio, Chiara

AU - Daniel, Rostislav

AU - Visaggio, Daniela

AU - Marsotto, Martina

AU - Visca, Paolo

AU - Bemporad, Edoardo

AU - Ascenzi, Paolo

AU - Capellini, Giovanni

AU - Sebastiani, Marco

AU - di Masi, Alessandra

N1 - Publisher Copyright: © 2021 Elsevier B.V.

PY - 2022/1/30

Y1 - 2022/1/30

N2 - Mechanical robustness, biocompatibility, and antibacterial performance are key features for materials suitable to be used in tissue engineering applications. In this work, we investigated the link existing between structural and functional properties of TiCu(Ag) thin films deposited by physical vapor deposition magnetron sputtering (MS-PVD) on Si substrates. Thin films were characterized by X-ray diffraction (XRD), nanoindentation, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). The TiCu(Ag) films showed complete amorphous structure and improved mechanical properties in comparison with pure Ti films. However, for contents in excess of 20% Ag we observed the appearance of nanometric Ag crystallite. The TiCu(Ag) thin films displayed excellent biocompatibility properties, allowing adhesion and proliferation of the human fibroblasts MRC-5 cell line. Moreover, all the investigated TiCu(Ag) alloys display bactericidal properties, preventing the growth of both Pseudomonas aeruginosa and Staphylococcus aureus. Results obtained from biological tests have been correlated to the surface structure and microstructure of films. The excellent biocompatibility and bactericidal properties of these multifunctional thin films opens to their use in tissue engineering applications.

AB - Mechanical robustness, biocompatibility, and antibacterial performance are key features for materials suitable to be used in tissue engineering applications. In this work, we investigated the link existing between structural and functional properties of TiCu(Ag) thin films deposited by physical vapor deposition magnetron sputtering (MS-PVD) on Si substrates. Thin films were characterized by X-ray diffraction (XRD), nanoindentation, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). The TiCu(Ag) films showed complete amorphous structure and improved mechanical properties in comparison with pure Ti films. However, for contents in excess of 20% Ag we observed the appearance of nanometric Ag crystallite. The TiCu(Ag) thin films displayed excellent biocompatibility properties, allowing adhesion and proliferation of the human fibroblasts MRC-5 cell line. Moreover, all the investigated TiCu(Ag) alloys display bactericidal properties, preventing the growth of both Pseudomonas aeruginosa and Staphylococcus aureus. Results obtained from biological tests have been correlated to the surface structure and microstructure of films. The excellent biocompatibility and bactericidal properties of these multifunctional thin films opens to their use in tissue engineering applications.

UR - http://www.scopus.com/inward/record.url?scp=85117338371&partnerID=8YFLogxK

U2 - 10.1016/j.apsusc.2021.151604

DO - 10.1016/j.apsusc.2021.151604

M3 - Article

VL - 573.2022

JO - Applied surface science

JF - Applied surface science

SN - 0169-4332

IS - 30 January

M1 - 151604

ER -